Characterization of persistent symptoms after SARS-CoV-2 infection

Post COVID 19 persistent symptoms

  • junnai carrillo
  • Vanesa Fridman
  • Daniel Stecher
Keywords: post covid, SARS-CoV-2, COVID-19, persistent symptoms

Abstract

Background: It is frequent that patients complain of persistent symptoms after an episode of COVID-19 infection, that worsened their quality of life

Aim: the aim of this study is to describe the main symptoms during a COVID-19 infection and persistent symptoms a month and three months after the episode. Our secondary objective is to describe the period between the COVID-19 episode and resuming work/ studies and exercise routine.  

Methods: this is a descriptive, observational study that included adults who underwent an episode of SARS-CoV-2 infection. Participants responded to an online survey. We include demographic and comorbidity data and symptoms during infection, and  one and three months after infection. 

Results: 308 people responded to the survey, frequent symptoms during the episode included myalgia and fever. A month after the episode, 96% complained of persistent symptoms, most frequently myalgia and fatigue. Three months after the episode 38.85% complained of  persistent symptoms , most frequently  fatigue and anosmia. Only 45.7% could resume work/ studies 10 days after the diagnosis, and 17% could resume exercise routine 10 days after the diagnosis. Conclusions: there is a high percentage of people who persisted with symptoms after a COVID-19 infection. We noticed symptoms improved over time, this finding  could be encouraged for patients who persist symptomatic after the episode.  

Downloads

Download data is not yet available.

Author Biographies

junnai carrillo

Médica Residente de tercer año, Enfermedades Infecciosas, División Infectología, Departamento de Medicina Interna, Hospital de Clínicas “José de San Martín”, Universidad de Buenos Aires, Argentina. Av. Córdoba 2351. Piso 3, Sala 2. CP 1120 CABA.

Vanesa Fridman

Médica Especialista en Enfermedades Infecciosas, Médica de Planta, División Infectología, Departamento de Medicina Interna, Hospital de Clínicas “José de San Martín”, Universidad de Buenos Aires, Argentina. Av. Córdoba 2351. Piso 3, Sala 2. CP 1120 CABA.

 

Daniel Stecher

Médico Especialista en Enfermedades Infecciosas, Jefe de División Infectología, Departamento de Medicina Interna, Hospital de Clínicas “José de San Martín”, Universidad de Buenos Aires, Argentina.

Av. Córdoba 2351. Piso 3, Sala 2. CP 1120 CABA.

References

Goërtz YMJ, Van Herck M, Delbressine JM, et al. Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome?. ERJ Open Res 2020; 6: 00542-2020. [https://doi.org/10.1183/23120541.00542-2020].
COVID Symptom Study. How Long Does COVID-19 Last? Available online at: https://covid19.joinzoe.com/post/covid-long-term?fbclid=IwAR1RxIcmmdL-EFjh_aI- .
Jacobs LG, GournaPaleoudis E, Lesky-Di Bari D, et al. Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection. PLoSOne. 2020;15(12):e0243882. Published 2020 Dec 11. doi:10.1371/journal.pone.0243882
Galván-Tejada CE, Herrera-García CF, Godina-González S, Villagrana-Bañuelos KE, Amaro JDL, Herrera-García K, Rodríguez-Quiñones C, Zanella-Calzada LA, Ramírez-Barranco J, Avila JLR, Reyes-Escobedo F, Celaya-Padilla JM, Galván-Tejada JI, Gamboa-Rosales H, Martínez-Acuña M, Cervantes-Villagrana A, Rivas-Santiago B, Gonzalez-Curiel IE. Persistence of COVID-19 Symptoms after Recovery in Mexican Population. Int J Environ ResPublicHealth. 2020 Dec 14;17(24):9367. doi: 10.3390/ijerph17249367. PMID: 33327641; PMCID: PMC7765113.
Ramani C, Davis Eric M , Kim J, Provencio J , Enfield J, Kadl A. Post-ICU COVID-19 Outcomes A Case Series. CHEST. January 2021
Nguyen Y, et al. Applicability of the CURB-65 pneumonia severity score for outpatient treatment of COVID-19. J infect 2020 :81 (3): e96-8.
Vandersteen C, Payne M, Dumas LE, Fernandez VM, Plonka A, Chirio D. Persistent olfactory complaints after COVID-19: a new interpretation of the psychophysical olfactory scores. Rhinology Online, Vol 4: 66 - 72, 2021. http://doi.org/10.4193/RHINOL/21.010
Wang D, Hu B, Hu C, et al. ClinicalCharacteristics of 138 HospitalizedPatientsWith 2019 Novel Coronavirus–InfectedPneumonia in Wuhan, China. JAMA. 2020;323(11):1061-1069.
Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. TheLancet. 2020;395(10223):507-513.
Li B, Yang J, Zhao F, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. Clinical research in cardiology : official journal of the German CardiacSociety. 2020.
Wang B, Li R, Lu Z, Huang Y. Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis. Aging. 2020;12.
Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. TheLancetRespiratory Medicine. 2020;8(5):475-481.
Wu Z, McGoogan JM. Characteristics of and ImportantLessonsFromthe Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases
Richardson S, Hirsch JS, Narasimhan M, et al. PresentingCharacteristics, Comorbidities, and OutcomesAmong 5700 PatientsHospitalizedWith COVID-19 in the New York City Area. Jama. 2020.
ICNARC reporton COVID-19 in criticalcare. 2020. www.icnarc.og.
Simonnet A, Chetboun M, Poissy J, et al. High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation. Obesity. n/a(n/a).
Helding, L., Carroll, T. L., Nix, J., Johns, M. M., LeBorgne, W. D., & Meyer, D. (2020). COVID-19 After Effects: Concerns for Singers. Journal of voice : official journal of the Voice Foundation, S0892-1997(20)30281-2. Advance online publication. https://doi.org/10.1016/j.jvoice.2020.07.032
Carfì A, Bernabei R, Landi F, fortheGemelliAgainst COVID-19 Post-AcuteCareStudyGroup. PersistentSymptoms in PatientsAfterAcute COVID-19. JAMA. 2020;324(6):603–605. doi:10.1001/jama.2020.12603
Ngai JC, Ko FW, Ng SS, To KW, Tong M, Hui DS. The long-term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status. Respirology. 2010; 15:543–50. https://doi.org/10.1111/j.1440-1843.2010.01720.x PMID: 20337995
Ahmed H, Patel K, Greenwood DC. Long-term clinical outcomes in survivors of severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus outbreaks after hospitalisation or ICU admission: A systematic review and meta-analysis. J RehabilMed. 2020 May 31; 52:jrm00063. https:// doi.org/10.2340/16501977-2694 PMID: 32449782
Zhou Y, Chi J, Lv W, Wang Y. Obesity and diabetes as high-risk factors for severe coronavirus disease 2019 (Covid-19). Diabetes Metab Res Rev. 2021;37(2):e3377. doi:10.1002/dmrr.3377.
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. TheLancet. 2020;395(10223):497-506.
ASEI 107 CARRILLO
Published
2021-11-26
How to Cite
carrillo, junnai, Fridman, V., & Stecher, D. (2021). Characterization of persistent symptoms after SARS-CoV-2 infection. Actualizaciones En Sida E Infectología, 29(107). https://doi.org/10.52226/revista.v29i107.95
Section
Original article