Occurrence of KPC-producing Morganella morganii brain abscess: microbiological and clinical description
Keywords:
morganella morganii, kpc, brain abscess
Abstract
Morganella morganii is a Gram-negative facultative anaerobic bacillus, which belongs to human gut commensal microbiota that can adquire resistance to multiple antibiotcs. We report here the isolation of blaKPC positive Morganella morganii isolate from a single patient and the concomitant clinical boarding and description. We present the clinical, microbiological and molecular caracterization of a brain abscess due KPC-producing Morganella morganii and the treatment applied.
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References
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Kariuki K, Diakhate MM, Musembi S, Tornberg-Belanger SN, Rwigi D, Mutuma T, Mutuku E, Tickell KD, Soge OO, Singa BO, Walson JL, Pavlinac PB, Kariuki S. Plasmid-mediated quinolone resistance genes detected in Ciprofloxacin non-susceptible Escherichia coli and Klebsiella isolated from children under five years at hospital discharge, Kenya. BMC Microbiol. 2023 May 13;23(1):129. doi: 10.1186/s12866-023-02849-2. PMID: 37173674; PMCID: PMC10182689.
Lee GC, Burgess DS. Treatment of Klebsiella Pneumoniae Carbapenemase (KPC) infections: a review of published case series and case reports. Ann Clin Microbiol Antimicrob 2012;11:32.
Liu, H., Zhu, J., Hu, Q., & Rao, X. (2016). Morganella morganii, a non-negligent opportunistic pathogen. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 50, 10–17. https://doi.org/10.1016/j.ijid.2016.07.006
Mbelle, N., Osei Sekyere, J., Feldman, C., Maningi, N. E., Modipane, L., & Essack, S. Y. (2020). Genomic analysis of two drug-resistant clinical Morganella morganii strains isolated from UTI patients in Pretoria, South Africa. Letters in applied microbiology, 70(1), 21–28. https://doi.org/10.1111/lam.13237
Mohammed Y, Gadzama GB, Zailani SB, Aboderin AO. Characterization of extended-spectrum beta-lactamase from Escherichia coli and Klebsiella species from North Eastern Nigeria. J Clin Diagnostic Res. 2016;10(2):DC07. [PMC free article] [PubMed] [Google Scholar]
Poirel L, Walsh TR, Cuvillier V, Nordmann P. Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis. 2011;70(1):119–123. doi: 10.1016/j.diagmicrobio.2010.12.002 [PubMed] [CrossRef] [Google Scholar]
Ponte, A., & Costa, C. (2015). Multiple Liver Abscesses due to Morganella morganii. Acta medica portuguesa, 28(4), 539.
Rozales, F. P., Ribeiro, V. B., Magagnin, C. M., Pagano, M., Lutz, L., Falci, D. R., Machado, A., Barth, A. L., & Zavascki, A. P. (2014). Emergence of NDM-1-producing Enterobacteriaceae in Porto Alegre, Brazil. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 25, 79–81. https://doi.org/10.1016/j.ijid.2014.01.005
Sheu CC, Chang YT, Lin SY, Chen YH, Hsueh PR. Infections caused by carbapenem-resistant Enterobacteriaceae: an update on therapeutic options. Front Microbiol. 2019;10:80.
Shi, H., Chen, X., Yao, Y., & Xu, J. (2022). Morganella morganii: An unusual analysis of 11 cases of pediatric urinary tract infections. Journal of clinical laboratory analysis, 36(5), e24399. https://doi.org/10.1002/jcla.24399
Published
2024-11-25
How to Cite
Vargas, J. M., Moreno Mochi, M. P., & Jure, M. (2024). Occurrence of KPC-producing Morganella morganii brain abscess: microbiological and clinical description . Actualizaciones En Sida E Infectología, 32(116). https://doi.org/10.52226/revista.v32i116.300
Section
Case Report
Copyright (c) 2024 Juan Martín Vargas, María Paula Moreno Mochi, María Jure
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
