Histoplasma capsulatum brain infection in an aids patient
Abstract
Introduction: Histoplasmosis is an endemic fungal infection worldwide distributed. It represents a serious problem in immunocompromised hosts which can develop a severe illness rapidly progressive. In this kind of patients the problem appears as a disseminated entity. The solitary compromise of the Central Nervous System is an extremely rare form in any kind of host, immunocompetent or immunocompromised.
Clinical case: An immunocompromised woman infected by hiv-aids, reactive HCV, brain histoplasmosis and disseminated cytomegalovirus disease is presented. She had not adherence to HAART. The disease appears like gastroenteritis with polymorphous skin lesions and general symptoms with progressive clinical worsening. She developed a severe neutropenia and sensory impairment and died at last after a long confine.
Conclusions: Disseminated histoplasmosis must be considered one of differential diagnostics in patients with aids and general symptoms. In spite of its rarity and difficult diagnosis, the compromise of the nervous system must be taken into account in endemic areas in immunocompromised patients since an earlier treatment becomes on a better prognostic.
Downloads
Copyright (c) 2023 Gisela Bejarano, Marcelo Gañete, Patricia Santillán, Cecilia Sampere, Daniel Sztokhamer
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
When an article is finally accepted in the journal, its authors assign their economic rights on a non-exclusive basis in favor of the editors, who allow reuse under an “Attribution-NonCommercial-ShareAlike 4.0 International” License (https://creativecommons.org/licenses/by-nc-sa/4.0/deed.es). This implies that the articles can be shared (copy and redistribute the material in any medium or format) and adapted (remix, transform and create another work from the material), as long as the authorship and the original source of publication (journal, publisher and URL of the work) are cited, they are not used for commercial purposes, and the same terms of the license are respected. It is requested to cite the original source of publication.
In addition, the acceptance of the article by the journal implies on the part of the authors the non-submission of the material to other journals or editorial bodies.
