COVID-19 in intensive care: which patients are most at risk of requiring mechanical ventilation?
DOI:
https://doi.org/10.52226/revista.v29i105.52Keywords:
COVID-19, SARS-CoV-2, mechanical ventilation, intensive careAbstract
Introduction: In severe COVID-19, identifying patients with a higher risk of mechanical ventilation (MV) helps to optimize management.
Materials and methods: Retrospective analysis of clinical-epidemiological characteristics of patients with COVID-19 admitted to ICU between March / September 2020. Descriptive statistics, univariate and multivariate analysis were used.
Results: 114 patients were admitted, 91 (79.8%) were men, mean age 54.6 ± 14.8 years. 66 (57.9%) were obese, 44 (38.6%) ≥60 years, 38 (33.3%) were hypertensive (33.3%) and 28 (24.6 %) diabetics. 39 (23%) had elevated ferritin, 62 (76.5%) had lymphopenia, and 33 (41.3%) had increased LDH. Overall mortality 34%. 72 patients (63.1%) required MV. The independent predictors of MV requirement in the multivariate analysis were male sex, age ≥60 years, diabetes, lymphopenia, and increased ferritin and LDH.
Conclusions: In patients with severe COVID-19, the independent predictors of the need for MV were male sex, age ≥ 60 years, diabetes, elevated levels of ferritin and LDH, and lymphopenia.
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