Vertical transmission of Dengue: Report of a neonatal case in a high complexity center in Guayaquil, Ecuador.
DOI:
https://doi.org/10.52226/tkk51m69Keywords:
Neonatal dengue, Vertical transmission, Capillary leak, NewbornAbstract
Vertical transmission of neonatal dengue presents a diagnostic challenge in hyperendemic areas such as Guayaquil. We report the case of a female neonate, the daughter of a pregnant woman who died from severe peripartum dengue. The patient was admitted with severe perinatal asphyxia, renal injury, and myocardial damage. On the fifth day, she developed fever and a rash, and the diagnosis was confirmed by a positive NS1 antigen test. During the critical phase, she developed hemoconcentration, thrombocytopenia, and pulmonary edema due to capillary leak. Grade 2 intraventricular hemorrhage was also documented. Dynamic fluid management allowed for stabilization without the need for blood products. The patient was discharged in stable condition after 14 days with multidisciplinary follow-up. Publicizing this case raises suspicion of dengue in an underreported age group; timely perinatal detection is crucial to prevent mortality associated with severe complications.
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Copyright (c) 2026 Andrés González, Joyce Andrade, Mildred Zambrano, Juan Chang
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