Chromoblastomycosis: a combination therapy approach

Abstract

Chromoblastomycosis is a chronic and subcutaneous mycosis caused by various dematiaceous

fungi, In Latin America, the most frequently found species are Fonsecaea pedrosoi and

Cladophialophora carrionii.

Treatment is a challenge because of the lack of response and recurrence in in some cases,

especially in patients with extensive and chronic lesions.

We report an individual with relapse of chromoblastomycosis (by Fonsecaea pedrosoi) in the

right lower limb, who had undergone incomplete treatment with terbinafine and itraconazole. The

 patient responded favorably to retreatment with itraconazole and terbinafine combined with

partial surgical resection of the lesion and skin grafting at the surgical site.